Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

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Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

BACKGROUND As there is limited information about the clinical signs of BSE and scrapie in goats, studies were conducted to describe the clinical progression of scrapie and BSE in goats and to evaluate a short clinical protocol for its use in detecting scrapie-affected goats in two herds with previously confirmed scrapie cases. Clinical assessments were carried out in five goats intracerebrally ...

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Transmissible Spongiform Encephalopathies

Neuronal death represents the primary pathology of neurodegenerative diseases such as Alzheimer's and Parkinson’s disease and Amyotrophic Lateral Sclerosis. These diseases usually present with a slow onset and a chronic progression. Various regions of the brain, spinal cord, or peripheral nerves may be affected, leading to functional impairment and neuron loss. Neurodegenerative diseases are of...

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Human Transmissible Spongiform Encephalopathies

Creutzfeldt-Jakob disease (CJD) is a rare and fatal human neurodegenerative condition characterized in most cases by a rapidly progressive dementia, myoclonus, and a periodic electroencephalogram (EEG). It is classified as a transmissible spongiform encephalopathy (TSE) because it causes characteristic spongy degeneration of the brain and can be transmitted to laboratory animals. TSEs also affe...

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Transmissible spongiform encephalopathies

Keywords Disease name and synonyms Included diseases Definition Pathogenesis Sporadic CJD Genetic forms of TSE Acquired forms of TSE Treatment Conclusion References Abstract Human prion diseases or transmissible spongiform encephalopathies (TSE) are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane prot...

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Transmissible spongiform encephalopathies.

Vet Med Today: Zoonosis Update 1705 T spongiform encephalopathies affect humans and other animals. Clinically, the diseases involve severe, progressive neurodegeneration with an invariably fatal outcome. The TSEs are linked by the unusual nature of their causative agent, which is believed to be a transmissible protein devoid of nucleic acid. This protein, known as a prion (a pseudoabbreviation ...

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ژورنال

عنوان ژورنال: BMC Veterinary Research

سال: 2010

ISSN: 1746-6148

DOI: 10.1186/1746-6148-6-13